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Article

Temperature-dependent hypermutational phenotype in recA mutants of Thermus thermophilus HB27.

Journal of bacteriology - 1 Aug 2003

Castán Pablo, Casares Lorena, Barbé Jordi, Berenguer José

Abstract excerpt

The recA gene from Thermus thermophilus HB27 was cloned and engineered to obtain insertion (recA::kat) and deletion (deltarecA) derivatives. Transcription of recA in this extreme thermophile was induced by mitomycin C, leading to the synthesis of a monocistronic mRNA. This DNA damage-mediated induction was dependent on the integrity of recA. In addition to UV sensitivity, the recA mutants of T. thermophilus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12897010
DOI: 10.1128/JB.185.16.4901-4907.2003
PMCID: PMC166453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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