Article
Cytokinesis mediated through the recruitment of cortexillins into the cleavage furrow.
The EMBO journal - 1 Feb 1999
Weber I, Gerisch G, Heizer C, Murphy J, Badelt K, Stock A, Schwartz J M, Faix J
Abstract excerpt
The fact that substrate-anchored Dictyostelium cells undergo cytokinesis in the absence of myosin II underscores the importance of other proteins in enabling the cleavage furrow to constrict. Cortexillins, a pair of actin-bundling proteins, are required for normal cleavage. They are targeted to the incipient furrow in wild-type and, more prominently, in myosin II-null cells. No other F-actin bundling or...
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