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Article

Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent.

Epilepsia - 1 Aug 2003

Santos Julia Belen, Schauwecker Paula Elyse

Abstract excerpt

PURPOSE: Previous studies have shown that the immunosuppressant cyclosporin A (CsA), a specific blocker of the mitochondrial permeability transition (MPT) pore, can dramatically ameliorate the selective neuronal necrosis resulting from ischemia-reperfusion, traumatic brain injury, and N-methyl-d-aspartate (NMDA)-evoked neurotoxicity. The purpose of this study was to determine whether two different...

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Source

Identifiers

PMID: 12887430
DOI: 10.1046/j.1528-1157.2003.66302.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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