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Article

Human alloantibody anti-Mart interferes with Mac-1-dependent leukocyte adhesion.

Blood - 1 Aug 2004

Sachs Ulrich J H, Chavakis Triantafyllos, Fung Lin, Lohrenz Alexander, Bux Jürgen, Reil Angelika, Ruf Andreas, Santoso Sentot

Abstract excerpt

The CD11b/CD18 integrin plays a crucial role in cell-cell adhesion processes. Recently, we described a case of severe neonatal alloimmune neutropenia (NAIN) caused by an alloantibody against a variant of the CD11b subunit (Mart alloantigen). Allele-specific transfected cells allowed us to demonstrate that an H61R point mutation is directly responsible for the formation of Mart epitopes. No difference in the...

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Identifiers

PMID: 15073035
DOI: 10.1182/blood-2003-11-3809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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