Article
Human alloantibody anti-Mart interferes with Mac-1-dependent leukocyte adhesion.
Blood - 1 Aug 2004
Sachs Ulrich J H, Chavakis Triantafyllos, Fung Lin, Lohrenz Alexander, Bux Jürgen, Reil Angelika, Ruf Andreas, Santoso Sentot
Abstract excerpt
The CD11b/CD18 integrin plays a crucial role in cell-cell adhesion processes. Recently, we described a case of severe neonatal alloimmune neutropenia (NAIN) caused by an alloantibody against a variant of the CD11b subunit (Mart alloantigen). Allele-specific transfected cells allowed us to demonst...
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