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Article

Reversal of mefloquine and quinine resistance in Plasmodium falciparum with NP30.

Antimicrobial agents and chemotherapy - 1 Aug 2003

Ciach Michelle, Zong Kathleen, Kain Kevin C, Crandall Ian

Abstract excerpt

Quinoline resistance in malaria is frequently compared with P-glycoprotein-mediated multidrug resistance (mdr) in mammalian cells. We have previously reported that nonylphenolethoxylates, such as NP30, are potential Plasmodium falciparum P-glycoprotein substrates and drug efflux inhibitors. We us...

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Identifiers

PMID: 12878495
DOI: 10.1128/AAC.47.8.2393-2396.2003
PMCID: PMC166084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12878495-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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