Article
Detection of mitochondrial DNA mutations in gestational trophoblastic disease.
Human mutation - 1 Aug 2003
Chiu Pui Man, Liu Vincent W S, Ngan Hextan Y S, Khoo Ui Soon, Cheung Annie N Y
Abstract excerpt
Mitochondrial DNA (mtDNA) mutations have been implicated in a wide range of human disease. However, its role in gestational trophoblastic disease remains unclear. In this study, the entire mitochondrial genome of 10 hydatidiform moles (HM) and one choriocarcinoma were examined by automated DNA sequencing after amplification by polymerase chain reaction. MtDNA sequences obtained separately from disease tissues (HM...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
