Article
Requirement for intracellular calcium modulation in zebrafish dorsal-ventral patterning.
Developmental biology - 15 Jul 2003
Westfall Trudi A, Hjertos Beth, Slusarski Diane C
Abstract excerpt
The phosphoinositide (PI) cycle is an important signal transduction pathway that, upon activation, generates intracellular second messengers and leads to calcium release. To determine whether PI cycle-mediated intracellular calcium release is required for body plan formation, we systematically dissect PI cycle function in the zebrafish (Danio rerio). We inhibit PI cycle function at three different steps and...
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