Article
Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication.
The Journal of biological chemistry - 10 Oct 2003
Park Sung Gyoo, Lee Soo Min, Jung Guhung
Abstract excerpt
The major role of hepatitis B virus polymerase (HBV pol) is polymerization of nucleotides, but it also participates in protein priming and the packaging of its own genome into capsids. Therefore, HBV pol may require many assistance factors for its roles. Previous reports have shown that Hsp60, a...
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