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Article

Hepatitis B virus replication could enhance regulatory T cell activity by producing soluble heat shock protein 60 from hepatocytes.

The Journal of infectious diseases - 15 Jul 2010

Kondo Yasuteru, Ueno Yoshiyuki, Kobayashi Koju, Kakazu Eiji, Shiina Masaaki, Inoue Jun, Tamai Keiichi, Wakui Yuta, Tanaka Yasuhito, Ninomiya Masashi, Obara Noriyuki, Fukushima Koji, Ishii Motoyasu, Kobayashi Tomoo, Niitsuma Hirofumi, Kon Satonori, Shimosegawa Tooru

Abstract excerpt

BACKGROUND: HBcAg-specific regulatory T (T(reg)) cells play an important role in the pathogenesis of chronic hepatitis B. Soluble heat shock proteins, especially soluble heat shock protein 60 (sHSP60), could affect the function of T(reg) cells via Toll-like receptor. METHODS: We analyzed the rela...

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Share to Antigen-Presenting Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chaperonin 60

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Source

Identifiers

PMID: 20533879
DOI: 10.1086/653496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20533879-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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