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Article

Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma.

Oncotarget - 18 Oct 2016

Zhang Jing, Zhou Xingchun, Chang Hulin, Huang Xiaojun, Guo Xu, Du Xiaohong, Tian Siyuan, Wang Lexiao, Lyv Yinghua, Yuan Peng, Xing Jinliang

Abstract excerpt

Heat shock protein 60 (Hsp60), a typical mitochondrial chaperone, is associated with progression of various cancers. However, its expression and significance in hepatocellular carcinoma (HCC) remain largely unclear. In the present study, the mRNA and protein expression of Hsp60 in HCC tissues were detected by quantitative RT-PCR (n=24), western blot (n=7), and immunohistochemical staining (n=295), respectively....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27677587
DOI: 10.18632/oncotarget.12185
PMCID: PMC5356605

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AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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