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Article

Aerobic growth deficient Haemophilus influenzae mutants are non-virulent: implications on metabolism.

International journal of medical microbiology : IJMM - 1 Jun 2003

Herbert Mark, Kraiss Anita, Hilpert Anna-Karina, Schlör Stefan, Reidl Joachim

Abstract excerpt

We investigated aerobic metabolism in Haemophilus influenzae to better understand its essential physiological growth pathways. We describe the isolation and characterization of transposon insertions leading to knockout mutations in lpdA, encoding dihydrolipoamide dehydrogenase. H. influenzae Rd lpdA::Tn10d-cat mutants were unable to grow aerobically and an H. influenzae type b lpdA::Tn10d-cat mutant was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12868651
DOI: 10.1078/1438-4221-00261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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