Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of the pentose phosphate pathway on metabolism and pathogenesis of Staphylococcus aureus

13 Jul 2023

Abstract excerpt

Staphylococcus aureus is an important pathogen that leads to significant disease through multiple routes of infection. We recently published a transposon sequencing (Tn-seq) screen in a mouse acute pneumonia model and identified a hypothetical gene (SAUSA300_1902, pgl) with similarity to a lactonase of Escherichia coli involved in the pentose phosphate pathway (PPP) that was conditionally essential. Limited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial biofilms and quorum sensing
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37440594
DOI: 10.1371/journal.ppat.1011531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of the pentose phosphate pathway on metabolism and pathogenesis of Staphylococcus aureusPMID 37440594Read ↗

Defining the roles of pyruvate oxidation, TCA cycle, and mannitol metabolism in methicillin resistance <i>Staphylococcus aureus</i> catheter-associated urinary tract infectionSemantic proximity Read ↗

Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.Semantic proximity Read ↗

Influence of the Alternative Sigma Factor RpoN on Global Gene Expression and Carbon Catabolism in Enterococcus faecalis V583Semantic proximity Read ↗

Virulence and MetabolismSemantic proximity Read ↗

Metabolic reprogramming and flux to cell envelope precursors in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibioticsSemantic proximity Read ↗

PhoU2 but Not PhoU1 as an Important Regulator of Biofilm Formation and Tolerance to Multiple Stresses by Participating in Various Fundamental Metabolic Processes in Staphylococcus epidermidis.Semantic proximity Read ↗

An integrated computational and experimental study to elucidate <i>Staphylococcus aureus</i> metabolismSemantic proximity Read ↗

Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate VirulenceSemantic proximity Read ↗

Insights Into the Impact of Small RNA SprC on the Metabolism and Virulence of Staphylococcus aureusSemantic proximity Read ↗

Amino Acid Catabolism in Staphylococcus aureus and the Function of Carbon Catabolite Repression.Semantic proximity Read ↗

Staphylococcus aureus encodes four differentially regulated pyruvate transporters.Semantic proximity Read ↗

Uracil restores susceptibility of methicillin-resistant Staphylococcus aureus to aminoglycosides through metabolic reprogrammingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.