Article
Mutational analysis of the Myocilin gene in patients with primary open-angle glaucoma in Morocco.
Ophthalmic genetics - 1 Sept 2003
Melki Rahma, Idhajji Abderrahmane, Driouiche Said, Hassani Moustafa, Boukabboucha Abdelaziz, Akhayat Omar, Garchon Henri, Belmouden Ahmed
Abstract excerpt
PURPOSE: To investigate the Myocilin (MYOC) gene for mutations and polymorphisms in patients with primary open-angle glaucoma (POAG) in Morocco. METHODS: Fifty-seven patients with severe POAG, who suffered from complete or almost complete visual field loss, were included in the study. The MYOC coding region, including exon I, exon II, and the coding part of exon III, were screened for sequence alteration using...
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