Article
Screening of CYP1B1 and MYOC in Moroccan families with primary congenital glaucoma: three novel mutations in CYP1B1.
Molecular vision - 2 Jul 2010
Hilal Latifa, Boutayeb Soraya, Serrou Aziza, Refass-Buret Loubna, Shisseh Hafsa, Bencherifa Fatiha, El Mzibri Mohammed, Benazzouz Bouchra, Berraho Amina
Abstract excerpt
PURPOSE: To investigate the contribution of cytochrome P4501B1 (CYP1B1) and myocillin (MYOC) mutations to primary congenital glaucoma (PCG) in Moroccan families. METHODS: This study included 90 unrelated families with PCG and 100 normal control individuals. Two previously reported CYP1B1 mutations (g.4339delG and p.G61E) were first screened by polymerase chain reaction-restriction fragment length polymorphism...
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