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Article

MYOC mutations in black south african patients with primary open-angle glaucoma: genetic testing and cascade screening.

Ophthalmic genetics - 1 Mar 2015

Williams Susan Eileen Isabella, Carmichael Trevor Robin, Wainstein Tasha, Hobbs Angela, Ramsay Michele

Abstract excerpt

BACKGROUND: Primary Open Angle Glaucoma (POAG) is an important cause of irreversible blindness in South Africa. Mutations in the MYOC gene are important in monogenic POAG. This study aimed to characterize potentially pathogenic MYOC mutations in this population. MATERIALS AND METHODS: Self-identified black South African POAG patients (215) and unaffected control participants (214) had ophthalmological...

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Source

Identifiers

PMID: 25330346
DOI: 10.3109/13816810.2014.972520

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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