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Article

IS981-mediated adaptive evolution recovers lactate production by ldhB transcription activation in a lactate dehydrogenase-deficient strain of Lactococcus lactis.

Journal of bacteriology - 1 Aug 2003

Bongers Roger S, Hoefnagel Marcel H N, Starrenburg Marjo J C, Siemerink Marco A J, Arends John G A, Hugenholtz Jeroen, Kleerebezem Michiel

Abstract excerpt

Lactococcus lactis NZ9010 in which the las operon-encoded ldh gene was replaced with an erythromycin resistance gene cassette displayed a stable phenotype when grown under aerobic conditions, and its main end products of fermentation under these conditions were acetate and acetoin. However, under...

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Identifiers

PMID: 12867459
DOI: 10.1128/JB.185.15.4499-4507.2003
PMCID: PMC165757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12867459-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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