Article
Effect of D-lactate on the physiological activity of the ArcB sensor kinase in Escherichia coli.
Journal of bacteriology - 1 Apr 2004
Rodriguez Claudia, Kwon Ohsuk, Georgellis Dimitris
Abstract excerpt
The Arc two-component system, comprising the ArcB sensor kinase and the ArcA response regulator, modulates the expression of numerous genes in response to the respiratory growth conditions. Under anoxic growth conditions ArcB autophosphorylates and transphosphorylates ArcA, which in turn represses or activates its target operons. The anaerobic metabolite D-lactate has been shown to stimulate the in vitro...
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