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Article

Sequence variation in hypoxia-inducible factor 1α (<i>HIF1A</i>): association with maximal oxygen consumption

29 Sept 2003

Abstract excerpt

Hypoxia-inducible factor 1 (HIF1) is a DNA transcription factor composed of two subunits, one of which is regulated by hypoxia (HIF1alpha, encoded by HIF1A). Genes regulated by HIF1 are involved in the processes of angiogenesis, erythropoiesis, and metabolism, making HIF1A a candidate gene in establishing maximal oxygen consumption (VO2 max) before and after aerobic exercise training. The purpose of the present...

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PMID: 12865501
DOI: 10.1152/physiolgenomics.00061.2003

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