Article
Gynecologic surgeries and risk of ovarian cancer in women with BRCA1 and BRCA2 Ashkenazi founder mutations: an Israeli population-based case-control study.
Journal of the National Cancer Institute - 16 Jul 2003
Rutter Joni L, Wacholder Sholom, Chetrit Angela, Lubin Flora, Menczer Joseph, Ebbers Sarah, Tucker Margaret A, Struewing Jeffery P, Hartge Patricia
Abstract excerpt
BACKGROUND: In the general population, the risk of developing ovarian cancer is reduced in women who have undergone tubal ligation, hysterectomy, or oophorectomy, although peritoneal cancer can arise after bilateral oophorectomy. In studies from genetic screening clinics, women with mutations in the breast and ovarian susceptibility genes BRCA1 and BRCA2 have been found to have a low risk of peritoneal carcinoma...
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