Article
Positive association of the HLA DMB1*0101-0101 genotype with rheumatoid arthritis.
Rheumatology (Oxford, England) - 1 May 1999
Perdriger A, Guggenbuhl P, Chalès G, Yaouanq J, Quelvennec E, Bonnard M N, Pawlotsky Y, Semana G
Abstract excerpt
OBJECTIVE: HLA DM is a non-classical major histocompatibility complex (MHC) class II molecule that has been shown to facilitate peptide loading with classical class II molecules. METHODS: In this study, we analysed the polymorphism in exon 3 of HLA DMA and DMB genes by a polymerase chain reaction-sequence-specific oligonucleotide probe method in 163 rheumatoid arthritis (RA) patients and 146 ethnically matched...
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