Positive association of the HLA DMB1*0101-0101 genotype with rheumatoid arthritis.

doi:10.1093/rheumatology/38.5.448

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Article

Positive association of the HLA DMB1*0101-0101 genotype with rheumatoid arthritis.

Rheumatology (Oxford, England) - 1 May 1999

Perdriger A, Guggenbuhl P, Chalès G, Yaouanq J, Quelvennec E, Bonnard M N, Pawlotsky Y, Semana G

Abstract excerpt

OBJECTIVE: HLA DM is a non-classical major histocompatibility complex (MHC) class II molecule that has been shown to facilitate peptide loading with classical class II molecules. METHODS: In this study, we analysed the polymorphism in exon 3 of HLA DMA and DMB genes by a polymerase chain reaction-sequence-specific oligonucleotide probe method in 163 rheumatoid arthritis (RA) patients and 146 ethnically matched...

Topics

Alleles
Arthritis, Rheumatoid
DNA Primers
Disease Susceptibility
Gene Frequency
Genotype
HLA-D Antigens
HLA-DR Antigens
Histocompatibility Antigens Class II
Histocompatibility Testing
Humans

Source

Open in PubMed

Identifiers

PMID: 10371284
DOI: 10.1093/rheumatology/38.5.448

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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