Article
HLA DRB1, DMA, and DMB gene polymorphisms in rheumatoid arthritis.
Human immunology - 1 Mar 1999
Reviron D, Tezenas du Montcel S, Foutrier C, Guis S, Benazet J F, Auquier P, Busson M, Roux H, Mercier P, Roudier J
Abstract excerpt
OBJECTIVE: To study the influence of DMA and DMB genes on susceptibility to Rheumatoid Arthritis (RA). METHODS: HLA-DRB1, DMA and DMB polymorphisms were defined by PCR SSOP in 203 European Mediterranean RA patients and 181 unrelated healthy controls. RESULTS: No significant difference in the phenotype frequencies of DMA and DMB alleles was observed between patients and controls. We found decreased frequencies of...
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