Article
Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2003
Bouchet Valérie, Hood Derek W, Li Jianjun, Brisson Jean-Robert, Randle Gaynor A, Martin Adèle, Li Zhong, Goldstein Richard, Schweda Elke K H, Pelton Stephen I, Richards James C, Moxon E Richard
Abstract excerpt
Otitis media, a common and often recurrent bacterial infection of childhood, is a major reason for physician visits and the prescription of antimicrobials. Haemophilus influenzae is the cause of approximately 20% of episodes of bacterial otitis media, but most strains lack the capsule, a factor k...
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