Article
Nontypeable Haemophilus influenzae: the role of N-acetyl-5-neuraminic acid in biology
1 Jan 2012
Abstract excerpt
Nontypeable Haemophilus influenzae (NTHi) is an exclusive human pathogen, which has evolved a number of unique mechanisms to survive within the human environment. An important part of this is the ability of the organism to take up and incorporate sialic acid into its surface structures. This protects the organism against host adaptive and innate immune factor as well as serving as a mechanism for sustaining...
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