Article
A triglyceride-raising APOA5 genetic variant is negatively associated with obesity and BMI in the Chinese population.
Obesity (Silver Spring, Md.) - 1 Oct 2010
Wu Cho-Kai, Chang Yi-Cheng, Hua Shih-Che, Wu Hon-Yen, Lee Wei-Jei, Chiang Fu-Tien, Hwang Juey-Jen, Lien Wen-Pin, Chuang Lee-Ming
Abstract excerpt
Apolipoprotein A-V (apo A-V) exerts a potent triglyceride (TG)-lowering effect through enhanced intravascular TG-hydrolysis with increased uptake of TG-derived free fatty acids into muscle and adipose tissue. Genetic variants in the APOA5 gene were strongly associated with plasma TG concentration...
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