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Gene Expression Profiling of Human Sarcomas: Insights into Sarcoma Biology

15 Oct 2005

Abstract excerpt

Sarcomas are a biologically complex group of tumors of mesenchymal origin. By using gene expression microarray analysis, we aimed to find clues into the cellular differentiation and oncogenic pathways active in these tumors as well as potential biomarkers and therapeutic targets. We examined 181 tumors representing 16 classes of human bone and soft tissue sarcomas on a 12,601-feature cDNA microarray. Remarkably,...

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PMID: 16230383
DOI: 10.1158/0008-5472.can-05-1699

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