Article
Glucose-6-phosphate dehydrogenase (G-6-PD) mutations in Mexico: four new G-6-PD variants.
Blood cells, molecules & diseases - 1 Jan 2000
Vaca Gerardo, Arámbula Eliakym, Monsalvo Alejandro, Medina Claudina, Nuñez Cristina, Sandoval Lucila, López-Guido Beatriz
Abstract excerpt
Screening for mutations at the G-6-PD gene by PCR-SSCP combined with restriction enzyme analysis and DNA sequencing was performed in nine G-6-PD deficient individuals with negative results for the presence of the most frequent G-6-PD mutations previously observed in Mexican population. The variants G-6-PD Valladolid(406T), G-6-PD Durham(713G), and G-6-PD Viangchan(871A) and four new G-6-PD mutant alleles were...
Topics
- Base Sequence
- DNA Mutational Analysis
- Genetic Testing
- Genetic Variation
- Glucosephosphate Dehydrogenase
- Humans
- Mexico
- Point Mutation