Article
An Overall View of the Functional and Structural Characterization of Glucose-6-Phosphate Dehydrogenase Variants in the Mexican Population.
International journal of molecular sciences - 11 Aug 2023
Hernández-Ochoa Beatriz, Ortega-Cuellar Daniel, González-Valdez Abigail, Martínez-Rosas Víctor, Morales-Luna Laura, Rojas-Alarcón Miriam Abigail, Vázquez-Bautista Montserrat, Arreguin-Espinosa Roberto, Pérez de la Cruz Verónica, Castillo-Rodríguez Rosa Angélica, Canseco-Ávila Luis Miguel, Vidal-Limón Abraham, Gómez-Manzo Saúl
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, affecting an estimated 500 million people worldwide, is a genetic disorder that causes human enzymopathies. Biochemical and genetic studies have identified several variants that produce different ranges of phenotypes; thus, depending on its severity, this enzymopathy is classified from the mildest (Class IV) to the most severe (Class I). Therefore,...
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