Article
Dose-dependent effects of strontium on osteoblast function and mineralization.
Kidney international - 1 Aug 2003
Verberckmoes Steven C, De Broe Marc E, D'Haese Patrick C
Abstract excerpt
BACKGROUND: Strontium-ranelate is now being used in the treatment of osteoporosis in elderly patients. As the majority of these patients already have a decreased renal function they are at an increased risk for accumulation of the element. Recent findings from epidemiologic studies in dialysis patients and experimental data obtained in a chronic renal failure (CRF) rat model established a dose-related multiphasic...
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