Article
Characterization of the human HOX 7 cDNA and identification of polymorphic markers.
Human molecular genetics - 1 Sept 1992
Padanilam B J, Stadler H S, Mills K A, McLeod L B, Solursh M, Lee B, Ramirez F, Buetow K H, Murray J C
Abstract excerpt
cDNA clones for a human HOX 7 gene obtained with homologous clones of Drosophila were used in human gene mapping studies. The human cDNA clone was isolated from a library constructed from human embryonic craniofacial material. The sequence of the cDNA demonstrates significant homology with mouse HOX 7. A search for RFLPs identified MboII and BstEII variants. A CA dinucleotide repeat with 5 alleles was also...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 4
- Cloning, Molecular
- DNA
- Deoxyribonucleases, Type II Site-Specific
- Drosophila
- Embryo, Mammalian
- Embryo, Nonmammalian