Article
The role of intermediate filaments in early Xenopus development studied by antisense depletion of maternal mRNA.
Development (Cambridge, England). Supplement - 1 Jan 1992
Heasman J, Torpey N, Wylie C
Abstract excerpt
The effects of depleting a maternal cytokeratin mRNA on the developing embryo are described. Cytokeratins are members of the intermediate filament family of cytoskeletal proteins, and are expressed in a cortical network of the superficial cytoplasm of the oocyte. After fertilisation, a new cortical network is built up, which comes to occupy only the most superficial cells of the blastula. The maternal cytokeratin...
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