Article
Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes.
The Journal of clinical endocrinology and metabolism - 1 Jul 2003
Motohashi Yoshiko, Yamada Satoru, Yanagawa Tatsuo, Maruyama Taro, Suzuki Ryuji, Niino Masaaki, Fukazawa Toshiyuki, Kasuga Akira, Hirose Hiroshi, Matsubara Koichi, Shimada Akira, Saruta Takao
Abstract excerpt
Type 1 diabetes mellitus is recognized as a T-cell-mediated autoimmune disease. Vitamin D compounds are known to suppress T-cell activation by binding to the vitamin D receptor (VDR); and thus, VDR gene polymorphisms may be related to T-cell-mediated autoimmune diseases. We, therefore, investigat...
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