Article
Estrogen receptor alpha gene polymorphisms and bone mineral density: haplotype analysis in women from the United Kingdom.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2001
Albagha O M, McGuigan F E, Reid D M, Ralston S H
Abstract excerpt
Genetic factors are important in the pathogenesis of osteoporosis and the estrogen receptor has been suggested as a possible candidate gene for regulation of bone mineral density (BMD). We investigated the relationship between PvuII, XbaI, and dinucleotide (TA)n repeat polymorphisms of the estrogen receptor alpha (ER-alpha) gene and BMD in a study of women from northeast Scotland in the United Kingdom. No...
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