Article
Pathogenesis of systemic lupus erythematosus.
Journal of clinical pathology - 1 Jul 2003
Mok C C, Lau C S
Abstract excerpt
The exact patho-aetiology of systemic lupus erythematosus (SLE) remains elusive. An extremely complicated and multifactorial interaction among various genetic and environmental factors is probably involved. Multiple genes contribute to disease susceptibility. The interaction of sex, hormonal milieu, and the hypothalamo-pituitary-adrenal axis modifies this susceptibility and the clinical expression of the disease....
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