Article
Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11).
Genes, chromosomes & cancer - 1 Nov 1992
Aman P, Ron D, Mandahl N, Fioretos T, Heim S, Arheden K, Willén H, Rydholm A, Mitelman F
Abstract excerpt
Most myxoid liposarcomas (MLS) are characterized cytogenetically by a t(12;16)(q13;p11). It is reasonable to assume that this translocation corresponds to the consistent rearrangement of one or two genes in 12q13 and/or 16p11, and that the loci thus affected are important in the normal control of...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- Blotting, Southern
- CCAAT-Enhancer-Binding Proteins
- Cell Transformation, Neoplastic
- Chromosomes, Human, Pair 12
- Chromosomes, Human, Pair 16
- DNA
- DNA-Binding Proteins
- Female
- Gene Rearrangement
- Humans
- Liposarcoma
- Male
- Middle Aged
- Molecular Sequence Data