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Long-term culture and differentiation of rat embryonic stem cell-like cells into neuronal, glial, endothelial, and hepatic lineages.

Stem cells (Dayton, Ohio) - 1 Jan 2003

Ruhnke Maren, Ungefroren H, Zehle G, Bader M, Kremer B, Fändrich F

Abstract excerpt

The in vitro differentiation of mouse embryonic stem cells into different somatic cell types such as neurons, endothelial cells, or myocytes is a well-established procedure. Long-term culture of rat embryonic stem cells is known to be hazardous, and attempts to differentiate these cells in vitro so far have been unsuccessful. We herein describe stable long-term culture of an alkaline phosphatase-positive rat...

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PMID: 12832696
DOI: 10.1634/stemcells.21-4-428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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