Article
From subgenome analysis to protein structure.
Current opinion in structural biology - 1 Jun 2003
Man Orna, Atarot Tal, Sadot Avital, Olender Tsviya, Lancet Doron
Abstract excerpt
Groups of related genes abound in large eukaryotic genomes. In such 'subgenomes', homology modeling carried out for a few genes will probably have relevance to the entire group. Subgenomes also afford unique ways of determining protein structural information. In addition to analyses based on the quantification of residue variability in paralogs, two-way comparisons, both within and among species, help to disclose...
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