Article
Pathways of removal of free DNA vector ends in normal and DNA-PKcs-deficient SCID mouse hepatocytes transduced with rAAV vectors.
Human gene therapy - 10 Jun 2003
Nakai Hiroyuki, Storm Theresa A, Fuess Sally, Kay Mark A
Abstract excerpt
Elucidation of the mechanisms of transformation of single-stranded (ss) recombinant adeno-associated virus (rAAV) vector genomes into a variety of stable double-stranded (ds) forms is key to a complete understanding of rAAV vector transduction in vivo. Ds monomer genome formation and cellular ds...
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