Is microsatellite mutational asymmetry detectable in allele frequency distributions?

Abstract excerpt

We explore the mutational processes giving rise to microsatellite diversity by analysing allele lengths in 6045 human microsatellite markers drawn from the CEPH panel. Assuming a general mutation-drift process generating this diversity, the bias of the mutation distribution cannot be directly estimated from such data. However, inferences can still be made about the degree and sign of the asymmetry of the mutation...

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