Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predictive value of expression of P53, Bcl‐2 and lung resistance‐related protein for response to chemotherapy in non‐small cell lung cancers

1 Apr 2003

Abstract excerpt

Chemoresistance is a major problem in the chemotherapy of non-small cell lung cancers (NSCLCs). Several mechanisms are thought to be involved in drug resistance, including those associated with apoptosis, drug transport and detoxification. Here, we investigated the predictive value of P53, Bcl-2 and lung resistance-related protein (LRP) expression for response to platinum-based chemotherapy, using transbronchial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cell death mechanisms and regulation
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12824911
DOI: 10.1111/j.1349-7006.2003.tb01453.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predictive value of expression of P53, Bcl‐2 and lung resistance‐related protein for response to chemotherapy in non‐small cell lung cancersPMID 12824911Read ↗

Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.Semantic proximity Read ↗

Increased ABCC2 expression predicts cisplatin resistance in non‐small cell lung cancerSemantic proximity Read ↗

miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2Semantic proximity Read ↗

p53-Dependent anticancer effects of leptomycin B on lung adenocarcinoma.Semantic proximity Read ↗

Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancerSemantic proximity Read ↗

Prognostic value of immunohistochemical expression of p53, bax, Bcl‐2 and Bcl‐x<sub>L</sub> in resected non‐small‐cell lung cancersSemantic proximity Read ↗

Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2.Semantic proximity Read ↗

Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells.Semantic proximity Read ↗

bcl-2 Protein in Non-Small-Cell Lung CarcinomaSemantic proximity Read ↗

Prognostic significance of mutant p53 protein, P-glycoprotein and glutathione S-transferase-pi in patients with unresectable non-small cell lung cancer.Semantic proximity Read ↗

The relationship between cisplatin - induced apoptosis and p53 , bcl - 2 and bax expression in human lung cancer cellsSemantic proximity Read ↗

Determinants of Response to the DNA Topoisomerase II Inhibitors Doxorubicin and Etoposide in Human Lung Cancer Cell LinesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.