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Clinical and genetic studies of ETV6/ABL1‐positive chronic myeloid leukaemia in blast crisis treated with imatinib mesylate

20 Jun 2003

Abstract excerpt

Most chronic myeloid leukaemia (CML) patients are genetically characterized by the t(9;22)(q34;q11), generating the BCR/ABL1 fusion gene. However, a few CML patients with rearrangements of 9q34 and 12p13, leading to ETV6/ABL1 chimaeras, have also been reported. Here we describe the clinical and genetic response to imatinib mesylate treatment of an ETV6/ABL1-positive CML patient diagnosed in blast crisis (BC). A...

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PMID: 12823349
DOI: 10.1046/j.1365-2141.2003.04391.x

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