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Article

Cytogenetic, fluorescence in situ hybridization, and genomic array characterization of chronic myeloid leukemia with cryptic BCR-ABL1 fusions.

Cancer genetics - 1 Jan 2000

Shao Lina, Miller Sue, Keller-Ramey Jennifer, Zhang Yang, Roulston Diane

Abstract excerpt

Chronic myeloid leukemia (CML) is characterized by the breakpoint cluster region (BCR)-Abelson murine leukemia (ABL1) fusion gene. In approximately 1% of CML cases, the Philadelphia chromosome associated with the BCR-ABL1 fusion gene is not present, and the BCR-ABL1 fusion gene is generated by cryptic insertion or sequential translocations. In this study, we describe the cytogenetic and molecular features of five...

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Source

Identifiers

PMID: 26186983
DOI: 10.1016/j.cancergen.2015.04.006

Genes

ABL1
BCR
IKZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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