Article
Chronic myeloid leukemia with e14a3 BCR-ABL transcript: analysis of characteristics and prognostic significance.
Leukemia & lymphoma - 1 Jan 2015
Gui Xiaomin, Zhang Yong, Pan Jinlan, Qiu Huiying, Cen Jiannong, Xue Yongquan, Chen Suning, Shen Hongjie, Yao Li, Zhang Jun, Wu Yafang, Chen Yan
Abstract excerpt
Chronic myeloid leukemia (CML) is characterized by Philadelphia chromosome (Ph) and BCR-ABL fusion genes. This study retrospectively analyzed 2381 CML patients with Ph chromosome confirmed by cytogenetics, Fluorescence in situ hybridization (FISH) or real-time quantitative polymerase chain reaction (Q-PCR). Among them, five CML patients without e13a2, e14a2 or e1a2 transcripts detected by Q-PCR were identified....
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