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Article

CD45 isoform expression in autoimmune myasthenia gravis.

Autoimmunity - 1 Mar 2003

Tackenberg B, Nitschke M, Willcox N, Ziegler A, Nessler S, Schumm F, Oertel W H, Hemmer B, Sommer N

Abstract excerpt

In myasthenia gravis (MG), humoral and cellular immune mechanisms are involved in the autoimmune pathogenesis. In this study, we investigated the role of the CD45 molecule in MG, having recently reported an association in multiple sclerosis. CD45, a protein-tyrosine phophatase receptor type C (PTPRC), is essential for both thymic selection and peripheral activation of T and B cells. Our aims were to determine (a)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12820694
DOI: 10.1080/0891693031000084369

Genes

PTPRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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