Article
T cell recognition of Epstein-Barr virus associated lymphomas.
Cancer surveys - 1 Jan 1992
Rickinson A B, Murray R J, Brooks J, Griffin H, Moss D J, Masucci M G
Abstract excerpt
Epstein-Barr virus, a lymphotropic herpesvirus of humans, has potent B cell growth transforming activity yet persists in the lymphoid tissues of most individuals as a lifelong asymptomatic infection. Virus induced B cell growth transformation in vitro is associated with the expression of a limited set of viral genes encoding six nuclear antigens (EBNA 1, 2, 3A, 3B, 3C and LP) and two latent membrane proteins (LMP...
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