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Article

Quantification of Human DNA in Feces as a Diagnostic Test for the Presence of Colorectal Cancer

1 Jul 2003

Abstract excerpt

Analysis of nuclear DNA extracted from stool specimens (1) is a recent addition to cancer diagnostics (2)(3)(4). Most studies have focused on the detection of sequence variations in tumor suppressor genes and oncogenes and on their correlation with clinical stage. In addition, however, the amount of human DNA in feces may be increased in individuals with colorectal cancer. Villa et al. (5) found that β-globin...

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PMID: 12816918
DOI: 10.1373/49.7.1185

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