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Article

High detection rates of colorectal neoplasia by stool DNA testing with a novel digital melt curve assay.

Gastroenterology - 1 Feb 2009

Zou Hongzhi, Taylor William R, Harrington Jonathan J, Hussain Fareeda Taher Nazer, Cao Xiaoming, Loprinzi Charles L, Levine Theodore R, Rex Douglas K, Ahnen Dennis, Knigge Kandice L, Lance Peter, Jiang Xuan, Smith David I, Ahlquist David A

Abstract excerpt

BACKGROUND & AIMS: Current stool DNA tests identify about half of individuals with colorectal cancers and miss most individuals with advanced adenomas. We developed a digital melt curve (DMC) assay to quantify low-abundance mutations in stool samples for detection of colorectal neoplasms and compared this test with other approaches. METHODS: We combined a melt curve assay with digital polymerase chain reaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 19026650
DOI: 10.1053/j.gastro.2008.10.023

Genes

KRAS
APC
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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