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Article

Enhanced retrieval of DNA from human fecal samples results in improved performance of colorectal cancer screening test.

The Journal of molecular diagnostics : JMD - 1 Nov 2004

Whitney Duncan, Skoletsky Joel, Moore Kent, Boynton Kevin, Kann Lisa, Brand Randall, Syngal Sapna, Lawson Michael, Shuber Anthony

Abstract excerpt

Colorectal cancer accounts for more than 10% of all cancer deaths but is curable, if detected early. We reported previously on a stool-based screening test in which DNA from stool samples is subjected to genome analysis; sensitivity of the test has been limited in part by inefficiency of retrieving DNA from stool. Our aim was to test the impact of a new purification method that would increase the yield of human...

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Identifiers

PMID: 15507679
DOI: 10.1016/S1525-1578(10)60536-3
PMCID: PMC1876426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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