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Computational Tools to Assist in Analyzing Effects of the SERPINA1 Gene Variation on Alpha-1 Antitrypsin (AAT).

Genes - 6 Mar 2024

Mróz Jakub, Pelc Magdalena, Mitusińska Karolina, Chorostowska-Wynimko Joanna, Jezela-Stanek Aleksandra

Abstract excerpt

In the rapidly advancing field of bioinformatics, the development and application of computational tools to predict the effects of single nucleotide variants (SNVs) are shedding light on the molecular mechanisms underlying disorders. Also, they hold promise for guiding therapeutic interventions and personalized medicine strategies in the future. A comprehensive understanding of the impact of SNVs in the SERPINA1...

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PMID: 38540399
DOI: 10.3390/genes15030340
PMCID: PMC10970068

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