Article
A combined comparative genomic hybridization and expression microarray analysis of gastric cancer reveals novel molecular subtypes.
Cancer research - 15 Jun 2003
Tay Su Ting, Leong Siew Hong, Yu Kun, Aggarwal Amit, Tan Soo Yong, Lee Chee How, Wong Keith, Visvanathan Jaya, Lim Dennis, Wong Wai Keong, Soo Khee Chee, Kon Oi Lian, Tan Patrick
Abstract excerpt
Comparative genomic hybridization (CGH), microsatellite instability (MSI) assays, and expression microarrays were used to molecularly subclassify a common set of gastric tumor samples. We identified a number of novel genomic aberrations associated with gastric cancer and discovered that gastric tumors could be grouped by their expression profiles into three broad classes: "tumorigenic," "reactive," and...
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