Article
A novel genomic classification system of gastric cancer via integrating multidimensional genomic characteristics.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Nov 2021
Wang Haiyong, Ding Yongfeng, Chen Yanyan, Jiang Junjie, Chen Yiran, Lu Jun, Kong Mei, Mo Fan, Huang Yingying, Zhao Wenyi, Fang Ping, Chen Xiangliu, Teng Xiaodong, Xu Nong, Lu Yimin, Yu Xiongfei, Li Zhongqi, Zhang Jing, Wang Haohao, Bao Xuanwen, Zhou Donghui, Chi Ying, Zhou Tianhua, Zhou Zhan, Chen Shuqing, Teng Lisong
Abstract excerpt
BACKGROUND: Gastric cancer (GC) is one of the leading causes of cancer deaths with high heterogeneity. There is currently a paucity of clinically applicable molecular classification system to guide precise medicine. METHODS: A total of 70 Chinese patients with GC were included in this study and whole-exome sequencing was performed. Unsupervised clustering was undertaken to identify genomic subgroups, based on...
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